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It functions as a cofactor for key enzymatic reactions involved in one-carbon metabolism, nucleic acid synthesis, and mitochondrial energy regulation

2.4.2 CHAC1 in neuroprotection and organ injury Similar to its role in stem cell fate, CHAC1/BOTCH exhibits a dual function in regulating neuroprotection and inflammation following neuronal damage and organ injury

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Table 2 The relationship between immune cells and ferroptosis mechanisms

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