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Thesis in Biochemistry: University of California, San Francisco Experientia

To further validate the ferroptosis-mediated synthetic lethality of ARID1A and c-MET, we established another ARID1A-isogenic cell model derived from the RKO CRC cell line, which has a frameshift mutation in ARID1A [30]

Bruderer R, Bernhardt OM, Gandhi T, Miladinovic SM, Cheng LY, Messner S, Ehrenberger T, Zanotelli V, Butscheid Y, Escher C, Vitek O, Rinner O, Reiter L

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells

In addition, for this variant, the thiolate-FAD charge transfer maximally accumulates at 0.8 s, a time frame that is roughly 10-fold slower than that of the U597C variant

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