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It is characterized by symptoms such as tingling (paraesthesia), numbness, pain, temperature sensitivity, and muscle weakness in the hands and feet and can spread throughout the body

Your doctor will typically monitor your response through clinical improvement and blood tests such as full blood count, rather than rechecking B12 levels after starting injections

If you experience worsening neurological symptoms such as increasing weakness, loss of balance, or new symptoms, this requires prompt medical assessment rather than being considered part of normal adjustment

This was established as an important research question to be funded as part of the James Lind Alliance priority-setting partnership with the Pernicious Anaemia Society

In some cases, recovery might take longer than expected

You can expect an initial test about a week to ten days after you start your injections to see how your body is responding