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Furthermore, there is a relatively increased excretion of 11-oxycorticoid metabolites (421), which are biologically inactive compounds

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To extend the NO release time and improve the controllability of NO release, various NO donors/precursors have been developed, including RONO 2 , RSNOs, NONOates, and metal NO complexes, which are further loaded into various organic and inorganic biomaterial carriers to create NO delivery systems