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A few tiny champagne-sized bubbles are usually inconsequential, but a large bubble should be expelled by flicking the syringe and gently pushing the plunger until the air is gone

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Where research is still evolving is in pinpointing cosmetic-specific outcomes (like exactly X% wrinkle reduction after Y drips)

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10.1016/S2352-4642(18)30385-7 52 HannaF.WuP.HealdA.FryerA