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R.PanS.CrapserJ.HammondM.JellisonE.et al

Peroxisomal H 2 O 2 metabolism is usually related to the regulation of peroxisomal functions and is also important for extra-peroxisomal redox targets, such as FOXO3, the master regulator of ROS

The cells' overall defense systems are essentially collapsing under the weight of the inflammation, leading to mitochondrial calcium overload and eventual energy failure

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Frandsen C.S., Dejgaard T.F., Holst J.J., Andersen H.U., Thorsteinsson B., Madsbad S