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Hold down the test button on the detector and listen for a beep

Nicotine promotes the local release of norepinephrine within body tissues and systemic release of epinephrine from the adrenal glands

Table 1 Demographic and clinical characteristics of RETUNE pilot study participants (intervention arm only) randomized between February and September 2025 in Switzerland (N=98) The most common reason for refusing all offered products was that the participants had no interest in quitting tobacco smoking (34/45

Each burns differently and brings its own flavor (or lack thereof)

Concerns over public backlash, political feasibility and potential cuts to programs funded by tobacco taxes are all factors

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