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anti-Polyglutamate chain (polyE), pAb (IN105) 868540-17-4 Antiproliferative and anticancer compound [3

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Description

Antiproliferative and anticancer compound [3

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anti-Polyglutamate chain (polyE), pAb (IN105) 868540-17-4 Antiproliferative and anticancer compound [3Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of ? and ? tubulin. Two different mechanisms can generate microtubule diversity: the expression of different ? and ? tubulin genes, referred to as tubulin isotypes, and the generation of posttranslational modifications (PTMs) on ? and ? tubulin. Tubulin PTMs include the well known acetylation or phosphorylation, and others that have so far mostly

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