mtDNA damage The most striking difference between mitochondria and other organelles is that they have a separate set of genetic materials (mtDNA) consisting of 13 protein-coding genes, 22 tRNA genes, and 2 rRNA genes, which assist in maintaining mitochondrial function
Recently, several bacterial LOXs have been reported to demonstrate a pronounced double dioxygenation activity (Kim et al
The Value of U.S
J Endocr Soc (2020) 4(9):bvaa075
Nevertheless, most individuals have DKD, which results in diseases such as anemia, nerve damage, and fatigue
In cancer cells, GLS supports the production of glutamate, which is vital for the synthesis of GSH, a major antioxidant that scavenges ROS, triggering oxidative stress and eventually leading to apoptosis (211)