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USA 104 , 672677 (2007)

Homocysteine catabolism is conducted by cystathionine -synthase (CBS), an enzyme dependent on pyridoxal-5-phosphate (derived from vitamin B 6 ), which allows the condensation of homocysteine with serine (Fig

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Cells were then treated with the indicated treatments as described in individual experiments in 100 l medium per well

The protonmotive force generated thereby drives protons through the F 0 F 1 ATP synthase, allowing condensation of a phosphate group to ADP, with the formation of ATP [23]

In spite of limitations to the generalizability of the current creatine finding, it suggests that investigators reporting creatine-normalized metabolites in AnxD studies also report appropriately water-normalized values or demonstrate equivalence of water-normalized creatine values in patients and controls