However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)
That enzyme is NNMT, nicotinamide N-methyltransferase
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High concentrations for IV use should be diluted in normal saline or another compatible IV fluid before administration
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Dave Asprey, founder of Bulletproof and a prominent biohacker, has discussed 5-Amino-1MQ in combination with other peptides, highlighting "a lot of buzz about this peptide especially in combination with the 5-amino 1MQ."[28] He suggests it for biohackers seeking metabolic hacks without extreme diets