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32, D258D261

Takemoto-Kimura S, Ageta-Ishihara N, Nonaka M, Adachi-Morishima A, Mano T, Okamura M, et al

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Murine studies with specific TP53 mutants have shown that preserving either apoptotic or cell cycle regulatory functions alone is sufficient to delay tumorigenesis compared to complete TP53 loss, highlighting the distinct and complementary contributions of these two processes (119, 120)