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Aquaporin-4 is the key regulator of water flow and K + uptake in the central nervous system (CNS) [65, 66]

At the same concentration of 580 M, Cu(OAc) 2 induced a higher upregulation of IL-1 than CuCl 2 , while CuCl 2 induced a higher upregulation of IL-8, HSPA1A and FOSL1 than Cu(OAc) 2

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