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The disruption of these interactions results in excessive reactive oxygen species generation, defective steroidogenesis, impaired quality control, and transcriptional dysregulation, ultimately driving oocyte deterioration and follicular failure

doi: 10.1038/s41598-021-92442-2 23 HorsfallLJBurgessSHallINazarethI

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Cochrane noted a signal of more non-fatal serious adverse events in stroke

Tang D, Chen X, Kang R, Kroemer G (2021) Ferroptosis: molecular mechanisms and health implications