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Deficiency of these two genes reduces the uptake of extracellular fatty acids, impairs fatty acid -oxidation and mitochondrial oxidative metabolism, and adversely affects the long-term survival of skin tissue-resident memory T cells following viral infection [53]

Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, et al

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These are: Rhodiola: a botanical that has been found to improve task performance and lower serum cortisol levels in 576mg doses63 Ginseng: a root that, according to a 2024 review, contains components that could be novel candidates for cognitive improvement in older individuals for their ability to improve [subjective memory impairment] cognition when taken in doses of 100600mg per day64 (Ashwagandha used to be part of the mix but has since been cut

It's not a large randomized controlled trial the field needs more of those but it adds real human evidence to a peptide that has been producing consistent results in preclinical research for years