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Occludin functions as a dynamic regulatory protein whose presence at the BBB is correlated with increased transendothelial electrical resistance and decreased paracellular permeability

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Enterohepatic circulation further influences LT4 metabolism, with conjugation via glucuronidation and sulfation in the liver, secretion into bile, and partial reabsorption by the intestinal flora (Eghtedari And Correa 2023)

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