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Detoxification Support One of glutathione's key roles is assisting the liver in detoxifying harmful substances
Abbreviations CQ: Chloroquine CSCs: Cancer stem cells ER: Estrogen receptor-alpha GPxs: Glutathione peroxidases GSH: Glutathione HCC: Hepatocellular carcinoma hiPSC-MSCs: Mesenchymal stem cells drived from human induced pluripotent stem cells IBC: Inflammatory breast cancer IH: Isorhamnetin LOH: Loss of heterozygosity MnSOD: Manganese superoxide dismutase NAC: N -acetylcysteine PHGPx: Phospholipid GPx ROS: Reactive oxygen species TNBC: Triple-negative breast cancer TFAP2C: Transcription factor AP-2 gamma References Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A
Of note, AML patients with high SLC7A11 mRNA expression exhibited a drastically lower overall survival than patients with low SLC7A11 expression [42, 43]
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Glutathione in Foods While your body doesnt efficiently absorb glutathione from food, consuming sulfur-rich foods can support its production
Further, nanoparticles were loaded with marine sulphated polysaccharide, known as poly(-amino ester) PPID nanoparticles which have capacity to respond to ROS, and release DOX in a regulated way
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