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Treatment of folate metabolism abnormalities in autism spectrum disorder

When purchasing supplements, the three natural forms and especially the coenzyme forms should be given preference where possible

Those with documented deficiency in B12, B1, or B6 Patients with peripheral neuropathy (tingling, numbness, burning extremities) Those with lower back pain and sciatica with a neurological component Diabetic patients especially those on metformin (B12 depletion) Strict vegans the only people with complete B12 dietary absence Elderly adults with impaired B12 absorption Post-gastric or intestinal surgery patients Who Should Use with Caution

doi: 10.1074/jbc.M805464200

Many standard supplements contain artificial binders, flavors, or flow agents like magnesium stearate that you may want to avoid while breastfeeding

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