Although the study in the International Journal of Andrology notes a small drop in T in men who quit smoking, Brahmbhatt points out that the positive impact of quitting vastly outweighs this short-lived side effect (1)
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Even a short time around secondhand smoke can cause damage
An alternative hypothesis is depicted on the right, in which inhalation of chemicals common in e-cigarette aerosols (propylene glycol, glycerin, nicotine, or THC) alters the inflammatory state of the lungs, including changing alveolar macrophages to a proinflammatory phenotype with the release of inflammatory cytokines (indicated by yellow circles), such that a second hit causes a pathologic inflammatory response
In fact, a study recently published in the August edition of the journal Addiction discovered that within a year of quitting smoking, ex-smokers experienced lower stress levels than they had when they were lighting up regularly