Any effect is generally modest and depends heavily on training quality, diet, sleep, and hormone status
Topical creams can be applied to the area to increase blood flow, which would temporarily reduce cellulite
Promote the use of fat tissue as energy
At a glance Drug / isotretinoin (Accutane), oral retinoid for severe nodular acne Supplement / green tea extract (GTE), standardized to EGCG (epigallocatechin gallate) Primary concern / additive hepatotoxicity at GTE doses 400 mg EGCG/day Secondary concern / CYP1A2 and CYP3A4 modulation may shift isotretinoin metabolism Dietary green tea risk / low, typical brewed cup contains 50 to 100 mg EGCG Monitoring required / LFTs (ALT, AST) at baseline and weeks 4, 8 per iPLEDGE protocol FDA DILI signal / GTE linked to drug-induced liver injury in 29 case reports reviewed by NIH LiverTox Recommendation / avoid concentrated GTE supplements during isotretinoin
When administered by qualified professionals, yes
The side effects of glutamine depletion using hydrolytic enzymes are too severe, and there isnt glutamine-specific hydrolytic enzyme yet, making it currently not a good approach for treating cancer patients
