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This not only enhances our comprehension of the effects of Pycnogenol in established fields but also opens avenues for exploring novel approaches to harness its potential benefits for human health

Additionally, hemin (a porphyria therapeutic agent) has been shown to upregulate GPX4 via the HO-1/NRF2 signaling pathway, thereby inhibiting oxidative stress and ferroptosis, which alleviates CIN (265)

Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinsons disease

Therefore, we aimed to examine the practical supplements for the prevention and management of migraine attacks

The blood-brain barrier and the regulation of amino acid uptake and availability to brain