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The study has enrolled 1,535 participants across 13 countries and is expected to be completed in early 2026, with topline results anticipated ahead of a potential FDA filing

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In the Phase III LIBERTY-UC and LIBERTY-CD studies, Zymfentra elicited higher rates of clinical remission than placebo in patients with moderate-to-severe UC and CD, respectively, following induction with intravenous infliximab

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In addition, researchers investigate its effects on nitric oxide pathways, epithelial stability, and cytokine balance across different experimental models