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Total RNA was isolated using Qiagen RNeasy mini kit (Cat # 74106), RNA sequencing libraries were prepared with Illumina-compatible NEBNext Ultra II Directional RNA Library Prep Kit (New England BioLabs, MA, USA) were carried out by Genotypic Pvt.Ltd

doi: 10.1126/science.1241165

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While not they are not used as frequently as antihistamines, LRAs potentially can prevent or decrease flare-ups in certain individuals

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