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189 During the maturation of RPE, PGC-1 increases the expression of antioxidant genes, including catalase (CAT), glutathione peroxidase (GPX)1, peroxiredoxin (PRDX) 3, SOD1, SOD2, and TXN2, and represses oxidant-mediated cell death in RPE

Ambroxol (Amb) Ambroxol, an active metabolite of bromhexine, is approved for the treatment of airway diseases in several countries