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When comparing EtOH-fed with CON-fed mice, EtOH feeding did not cause changes in liver mRNA levels of three regulators, namely Srebp1, Ppar and Pgc-1 in either WT or KO mice (Fig

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It was more effectively activated by elevated levels of GSH in H1299 lung cancer cells than that in normal lung fibroblasts WI38 cells, releasing reactive alkoxyamines to capture AP sites, blocking APE1 repair, and leading to lung cancer cell death in vitro