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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Gwyer D, Wragg NM, Wilson SL

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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies