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(126) used a clinical cohort of 42 RA patients and 10 healthy controls found that RA patients exhibit clear gut microbiota dysbiosis, and the Clostridium metabolite vitamin K2 (VitK2) was enriched

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The protein concentration of the samples was determined using biocinchoninic acid (BC) Assay (Omnilabo, Veenendaal, the Netherlands)

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MenSC-derived ECM1 inhibits HSC activation and alleviates liver fibrosis in vivo and in vitro As rec-ECM1 therapy failed to alleviate liver fibrosis in mice, we used MenSCs that could home to the injured area to continuously express exogenous ECM1