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Elevated levels of glutamine, which is the end product of ammonia detoxification, is a key factor in both hepatic encephalopathy and ammonia-related neurotoxicity 12

Reconstituted solutions should be protected from reducing agents (such as DTT or beta-mercaptoethanol), which can cleave the disulfide bond and disrupt the active conformation

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A., Chauvin, A., Pascaud, F., Kellenberger, S

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