(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A
10.1016/j.redox.2018.01.008 22 CostantinoC
At BioRestore, peptide protocols are designed and guided by experienced clinicians to ensure theyre used safely, effective and for the right reasons
The Broad Institute CMap provides powerful data but uses specific cell lines and conditions that may not perfectly represent all tissue types
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He takes the time to thoroughly understand your condition and collaborates with you to develop a tailored treatment plan
