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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1
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Search strategies incorporated combinations of keywords and subject headings including BPC-157, PLD-116, PL-10, PL 14736, and body protective compound, and were tailored to each database
Preclinical research has also observed downregulation of pro-inflammatory cytokines including TNF-, IL-6, and IL-1, alongside modulation of NF-B signalling pathways positioning GHK-Cu as a subject of interest in inflammatory resolution research
Serum trace elements profile in Graves' disease patients with or without Orbitopathy in Northeast China
