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Description

Uridine is a small molecule made up of uracil and ribose, which is widely present in organisms and plays an important role in RNA and glycogen synthesis 21,22,23

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This NAD+ elevation activates sirtuins (particularly SIRT1), enhances mitochondrial function, and preserves methylation capacity by reducing S-adenosylmethionine (SAM) consumption

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A recent comprehensive bioinformatics analysis combined with a weighted gene correlation network analysis based on three independent GEO datasets showed that the FABP1 and PPAR-related signaling pathways were involved in IgAN pathogenesis [274]

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