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If the enzyme is active, it generates NADPH, which fluoresces under UV light

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In one study, 12 weeks of aerobic exercise in older rats restored PGC-1 and TFAM levels to above those of young untrained controls

Briefly, SOD converts superoxide anions to hydrogen peroxide and oxygen, which is then detoxified to water by catalase

It is an anatomically small brain region that contains widespread projections to multiple brain regions, thus activating this single site has the potential to result in widespread brain activation [93]