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The central tobacco factory once stood in what is now the Plaza Cristo de Burgos but by the 18th century, as demand for tobacco products grew, it became apparent Seville needed a new location for production

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Nicotine & Tobacco Research 2005;7:85970

Follow me on Twitter @drClaire About the Author Claire McCarthy, MD, Former Senior Faculty Editor, Harvard Health Publishing Disclaimer: As a service to our readers, Harvard Health Publishing provides access to our library of archived content

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Centers for Disease Control and Prevention) Parents Against Vaping E-Cigarettes website (Parents Against Vaping E-Cigarettes) Truth Initiative website (Truth Initiative) Vaping Prevention Resources (U.S