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The administration of candesartan is sufficient to block the isolation stress (24h isolation in individual metabolic cages)-induced increased binding of AT 1 R to PVN and to reduce the HPA response to stress (157)( Table 4 )
Conditions like Wilson's disease, a genetic disorder where the body cannot properly excrete excess copper, are an absolute contraindication
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It didnt make our list because the serving size is three larger-than-usual capsules, and this is a less appealing daily dose