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They appear after each dose increase, peak during the first week at the new dose, and gradually subside over 2 to 4 weeks

Falutz J, et al

Notably, germline EGFR T790M has not been reported in patients of East Asian ethnicity with lung cancer despite the high prevalence of somatic EGFR mutations in this population

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The general public may not always be able to distinguish between regulated and unregulated products

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