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For oral supplementation, 250 to 500 mg per day is the commonly studied range

alpha-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults

As always, we recommend a consultation with a doctor to determine whether these treatments are suitable for you

Full results develop over 12 weeks of consistent use

When its depleted

So, if you are eating a varied diet and do not have a laboratory-documented vitamin B12 deficiency, you do not need additional supplementation. However, she explains people who subscribe to strict vegan or vegetarian diets are much more likely to be at risk of vitamin B12 deficiency, and they should take supplemental B12, especially when pregnant or trying to become pregnant