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Yoshino M, Yoshino J, Kayser BD, et al

[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing

doi: 10.1111/andr.12124 72 MendiolaJJrgensenNAnderssonA-MCalafatAMYeXRedmonJBet al

For example, 5 subunit expression, which is implicated in learning and memory function, is increased in the pyramidal layer and oriens of the CA1 subregion

A., Cuddy, M