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The rate-limiting step in GSH synthesis is cysteine availability, regulated predominantly by the excitatory amino acid carrier 1 (EAAC1) transporter in neurons

Kuzyk, A

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Cognitive decline in Parkinson disease

Jiang F, DeSilva S, et al

In the drug metabolism studies from Manchester, UK (Table 1) , heightened theophylline clearance was the predominant finding in patients with idiopathic or alcoholic disease (18), indicating induction of CYP1A (70) - as by C18:2 fatty acids (eg in corn, peanut or linseed oil), polycyclic aromatic hydrocarbons and halogenated hydrocarbons (94)