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These include: Pain, redness, or swelling at the injection site Bruising or hardening of tissue (induration) Itching or warmth around the injection area Temporary discolouration of the skin These localised reactions typically resolve within 2472 hours

39 Studies have shown some chondroprotective and proliferative effects of PRP, as per Spreafico et al

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In addition, Due to its rapid metabolism, LA in tissues exists in limited quantities [56]