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Laboratory studies have continued to investigate its role in sleep-wake cycle regulation and its interactions with endogenous sleep-promoting systems

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2-cyano-3,12 dioxooleana-1,9 diene-28-imidazolide (CDDO-Im) and 2-cyano-3,12 dioxooleana-1,9, diene-28-methyl ester (CDDO-Me) induce caspase-independent cell death in pancreatic cancer in vitro and prevent the growth of pancreatic cancer xenografts in vivo

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Best Pract Res Clin Endocrinol Metab 35:101568