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Migration of fibroblast to area of injury is an important step in the recovery of wound that depends on actin protein [13]

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A transwell 3D liver co-culture model including non-parenchymal cells and human primary hepatocytes showed that treatment with TVX 25 M resulted in increased LDH release after 8 days with associated decrease in cellular viability 39

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Several iterations between auto- and manual-refinements were conducted for optimisation