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SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

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However, what happens during the course of the disease remains to be elucidated, as contradictory studies in rodent models of the disease either show an abnormal expression of endogenous autophagic markers, accumulation of autophagosomes, and decreased levels of beclin-1 [86] or show no changes in these and in additional autophagy markers [88]

doi: 10.3390/ijms24098325

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