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The total radioactivity concentrations in the kidney, liver, stomach wall, thymus, spleen, intestine, lung, skin, and body fat were reduced by approximately 50% compared with the peak concentration in the same tissue (1 h after administration)
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Our results suggest that both increased S -glutathionylation processes and suppressed de-glutathionylation reactions contribute to hepatic S -glutathionylation in NAFLD
Loss of cGAS abolished senescence phenotypes and senescence-associated -galactosidase (SA--Gal) activity, suggesting that cGAS is essential for cellular senescence (Yang et al., 2017)