These include Systemic Lupus Erythematous (SLE), mixed connective tissue disease, Sjogren's syndrome, scleroderma, polymyositis, CREST syndrome, and neurologic SLE
A review of human studies suggests that methionine, choline, folic acid, vitamin B2, B6, B12 and zinc may be essential to increase arsenic metabolism and reduce toxicity of arsenic within the human body (Sijko and Kozlowska, 2021)
However, the commercial availability of -EC remains limited owing to its complex chemical synthesis from glutamate and cysteine
J Cell Mol Med 8:20112, PMID: 15256068 Aracena-Parks P, Goonasekera SA, Gilman C, Dirksen RT, Hidalgo C, Hamilton SL (2006) Identification of cysteines involved in S -nitrosylation, S -glutathionylation, and oxidation to disulfides in RyR1
doi: 10.1016/j.ymgme.2015.06.004 17
Mar 4;362(9):779-89