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4 The pH variation of HA /A 2 buffer systems, such as phosphate, is three times that value

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

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Receptor activation stimulates GH release from the pituitary via two mechanisms: amplifying GHRH-driven GH pulses and inhibiting somatostatin tone