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Furthermore, NADPH is replenished by the isocitrate dehydrogenase (IDH1/IDH2) branch of the citric acid cycle (TCA cycle), malic enzyme (ME1), and one-carbon metabolism (such as the folate cycle) depending on cell type or nutritional status

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There is some anecdotal evidence

Such formulations can be readily prepared simply by dissolving niclosamide powder into buffered aqueous solution, where dissolution times to relative equilibrium take 1hr in stirred vials (as in Figure 5 )

Artificial mitochondria transfer: current challenges, advances, and future applications