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Natural interventions like exercise produce acute BDNF spikes within minutes that last up to 24 hours, while sustained lifestyle changes (regular exercise, diet optimization) produce baseline elevation over several weeks

The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane

DOI Pickart L, Vasquez-Soltero JM, et al

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doi: 10.1016/j.pharmthera.2021.107832 199 TakakuraSToyoshiTHayashizakiYTakasuT