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Key considerations for IV dosage include: The severity of the Vitamin B12 deficiency The presence of any underlying medical conditions that may affect B12 absorption The patients overall health status and response to initial treatment Clinical Scenarios for IV Administration IV Vitamin B12 is used for severe deficiencies or when other methods fail

(PubMed) de Batlle J, Ferrari P, Chajes V, et al

Fluid retention and edema: During treatment with glucocorticoids and diclofenac, edema and fluid retention have been observed so the formula must be used with caution in patients with a history of decompensation, hypertension or other factors predisposing to fluid retention

However, it also have potential side effects which must be considered

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We can determine if an alternate type may decrease unpleasant early symptoms