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Plasma urea values were higher at d 10 prepartum and at calving day

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They are not hormones

Their actions can be exerted on other neurons as modulators of signaling, or on non-neuronal cells as signaling molecules

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Physical dependence is a state that develops as a result of a physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug