Miscarriage is increasingly connected to platelet hyperaggregability, also known as sticky platelet syndrome (SPS) (179)
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It has recently been recognized that natural killer cells ( NK) are very important in promoting fetal development because they secrete growth promoting factors
For plasma preparation, EDTA and heparinized blood was centrifuged (1,950 x g, 15 min, Varifuge 3.0, Heraeus, Hanau, Germany) and the obtained plasma was stored at -80C until further analysis